The Role of Anti-Müllerian Hormone (AMH) in Assessing Ovarian Reserve | Zendy

Nam D. Tran | Zendy; Marcelle I. Cedars | Zendy; Mitchell P. Rosen | Zendy

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The Role of Anti-Müllerian Hormone (AMH) in Assessing Ovarian Reserve

Author(s) -

Nam D. Tran,

Marcelle I. Cedars,

Mitchell P. Rosen

Publication year - 2011

Publication title -

the journal of clinical endocrinology and metabolism

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.206

H-Index - 353

eISSN - 1945-7197

pISSN - 0021-972X

DOI - 10.1210/jc.2011-0368

Subject(s) - anti müllerian hormone , ovarian reserve , müllerian mimicry , hormone , medicine , biology , infertility , pregnancy , genetics , pathology

Anti-müllerian hormone (AMH) has been suggested as a marker for the quantity of oocytes remaining within the ovaries (ovarian reserve). It was shown to correlate with antral follicle counts (AFC), outcomes from ovarian stimulation, and onset of menopause. Thus, AMH was previously considered to be the ideal marker of ovarian reserve because it is exclusively produced by granulosa cells and is the only marker that was thought to be stable throughout the menstrual cycle. However, recent studies demonstrate fluctuations in AMH levels during the menstrual cycles, questioning the utility of AMH as a marker of oocyte quantity.

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