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Cardiac Dimensions Are Largely Determined by Dietary Salt in Patients with Primary Aldosteronism: Results of a Case-Control Study
Author(s) -
Eduardo Pimenta,
Richard D. Gordon,
Ashraf Ahmed,
Diane Cowley,
Rodel Leano,
Thomas H. Marwick,
Michael Stowasser
Publication year - 2011
Publication title -
the journal of clinical endocrinology and metabolism
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.206
H-Index - 353
eISSN - 1945-7197
pISSN - 0021-972X
DOI - 10.1210/jc.2011-0354
Subject(s) - primary aldosteronism , interventricular septum , medicine , aldosterone , cardiology , blood pressure , essential hypertension , diastole , body mass index , left ventricular hypertrophy , pathogenesis , muscle hypertrophy , mass index , cardiac fibrosis , endocrinology , fibrosis , ventricle
Animal studies have demonstrated that dietary sodium intake is a major influence in the pathogenesis of aldosterone-induced effects in the heart such as left ventricular (LV) hypertrophy and fibrosis. LV hypertrophy is an important predictor for cardiovascular morbidity and mortality.

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