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MiR-1 Is a Tumor Suppressor in Thyroid Carcinogenesis Targeting CCND2, CXCR4, and SDF-1α
Author(s) -
Vincenza Leone,
Daniela D’Angelo,
Ileana Gabriela Sanchez Rubio,
Paula Mussnich de Freitas,
Antonio Federico,
Marianna Colamaio,
Pierlorenzo Pallante,
Geraldo MedeirosNeto,
Alfredo Fusco
Publication year - 2011
Publication title -
the journal of clinical endocrinology and metabolism
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.206
H-Index - 353
eISSN - 1945-7197
pISSN - 0021-972X
DOI - 10.1210/jc.2011-0345
Subject(s) - thyroid , thyroid carcinoma , cancer research , thyroid cancer , carcinogenesis , stromal cell derived factor 1 , biology , cyclin d2 , cxcr4 , metastasis , stromal cell , papillary thyroid cancer , medicine , cancer , endocrinology , chemokine , cell cycle , receptor , cyclin
Micro-RNA have emerged as an important class of short endogenous RNA that act as posttranscriptional regulators of gene expression and are constantly deregulated in human cancer. MiR-1 has been found down-regulated in lung, colon, and prostate cancer.

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