Gonadal Pathology and Tumor Risk in Relation to Clinical Characteristics in Patients with 45,X/46,XY Mosaicism | Zendy

Martine Cools | Zendy; J. Pleskacova | Zendy; Hans Stoop | Zendy; Piet Hoebeke | Zendy; Erik Van Laecke | Zendy; Stenvert L. S. Drop | Zendy; Jan Lebl | Zendy; J. Wolter Oosterhuis | Zendy; Leendert H. J. Looijenga | Zendy; Katja P. Wolffenbuttel | Zendy

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Gonadal Pathology and Tumor Risk in Relation to Clinical Characteristics in Patients with 45,X/46,XY Mosaicism

Author(s) -

Martine Cools,

J. Pleskacova,

Hans Stoop,

Piet Hoebeke,

Erik Van Laecke,

Stenvert L. S. Drop,

Jan Lebl,

J. Wolter Oosterhuis,

Leendert H. J. Looijenga,

Katja P. Wolffenbuttel

Publication year - 2011

Publication title -

the journal of clinical endocrinology and metabolism

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.206

H-Index - 353

eISSN - 1945-7197

pISSN - 0021-972X

DOI - 10.1210/jc.2011-0232

Subject(s) - gonadoblastoma , gonad , malignancy , germ cell tumors , disorders of sex development , biopsy , histology , medicine , development of the gonads , pathology , biology , testosterone (patch) , gynecology , physiology , oncology , gene , biochemistry , chemotherapy , karyotype , chromosome

Gonadectomy is avoided whenever possible in boys with 45,X/46,XY. However, no clinical markers are currently available to guide clinicians in predicting gonadal tumor risk or hormone production.

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