Consequences of Craniopharyngioma Surgery in Children | Zendy

Hermann L. Müller | Zendy

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Consequences of Craniopharyngioma Surgery in Children

Author(s) -

Hermann L. Müller

Publication year - 2011

Publication title -

the journal of clinical endocrinology and metabolism

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.206

H-Index - 353

eISSN - 1945-7197

pISSN - 0021-972X

DOI - 10.1210/jc.2011-0174

Subject(s) - craniopharyngioma , medicine , quality of life (healthcare) , radiation therapy , pituitary neoplasm , resection , pituitary tumors , surgery , pediatrics , pituitary gland , nursing , hormone

Childhood craniopharyngioma, a rare embryogenic tumorous malformation of the sellar region, is characterized by survival rates ranging from 91 to 98%. However, quality of survival is frequently impaired due to proximity to optical, pituitary, and hypothalamic structures. Long-term sequelae substantially reduce the quality of life of approximately 50% of long-term survivors, notably extreme obesity owing to hypothalamic involvement and/or surgical- or radiation-induced lesions.

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