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Changes in Reproductive Hormone Concentrations Predict the Prevalence and Progression of the Frailty Syndrome in Older Men: The Concord Health and Ageing in Men Project
Author(s) -
Thomas G. Travison,
AnhHoa Nguyen,
Vasi Naganathan,
Fiona Stanaway,
Fiona Blyth,
Robert G. Cumming,
David G. Le Couteur,
Philip N. Sambrook,
David J. Handelsman
Publication year - 2011
Publication title -
the journal of clinical endocrinology and metabolism
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.206
H-Index - 353
eISSN - 1945-7197
pISSN - 0021-972X
DOI - 10.1210/jc.2011-0143
Subject(s) - medicine , testosterone (patch) , ageing , dihydrotestosterone , estrone , frailty syndrome , sex hormone binding globulin , androgen , body mass index , cohort , androgen deficiency , estrogen , endocrinology , gerontology , hormone , longitudinal study , frailty index , pathology
Frailty, a syndrome of multiple morbidity, weakness, and immobility in aging, is an increasingly urgent threat to public health. Single measures of low serum androgen have been associated with frailty in men, but the contributory role of hormonal changes with time is unassessed.

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