Open AccessLong-Term Safety of Growth Hormone Replacement after CNS Irradiation
Author(s) -
S. Mackenzie,
Timothy E. Craven,
H. Rao Gattamaneni,
R. Swindell,
Stephen M. Shalet,
G. Brabant
Publication year - 2011
Publication title -
the journal of clinical endocrinology and metabolism
Language(s) - English
Resource type - Journals
eISSN - 1945-7197
pISSN - 0021-972X
DOI - 10.1210/jc.2011-0112
Subject(s) - medicine , radiation therapy , incidence (geometry) , retrospective cohort study , magnetic resonance imaging , medical record , surgery , radiology , physics , optics
Radiotherapy is a central component in the treatment of many brain tumors, but long-term sequelae include GH deficiency and increased risk of secondary neoplasms. It is unclear whether replacement therapy with GH (GHRT) further increases this risk.
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom