Decreased Circulating Soluble Tie2 Levels in Preeclampsia May Result from Inhibition of Vascular Endothelial Growth Factor (VEGF) Signaling | Zendy

Joyce F. Sung | Zendy; Xiujun Fan | Zendy; Sabita Dhal | Zendy; Bonnie K. Dwyer | Zendy; Anahita Jafari | Zendy; Yasser Y. ElSayed | Zendy; Maurice L. Druzin | Zendy; Nihar R. Nayak | Zendy

Open Access

Decreased Circulating Soluble Tie2 Levels in Preeclampsia May Result from Inhibition of Vascular Endothelial Growth Factor (VEGF) Signaling

Author(s) -

Joyce F. Sung,

Xiujun Fan,

Sabita Dhal,

Bonnie K. Dwyer,

Anahita Jafari,

Yasser Y. ElSayed,

Maurice L. Druzin,

Nihar R. Nayak

Publication year - 2011

Publication title -

the journal of clinical endocrinology and metabolism

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.206

H-Index - 353

eISSN - 1945-7197

pISSN - 0021-972X

DOI - 10.1210/jc.2011-0063

Subject(s) - angiopoietin receptor , preeclampsia , vascular endothelial growth factor , angiopoietin , endocrinology , medicine , placenta , vascular endothelial growth factor a , kinase insert domain receptor , matrix metalloproteinase , placental growth factor , basal (medicine) , angiogenesis , pregnancy , fetus , biology , vegf receptors , insulin , genetics

Recent studies have found dysregulation in circulating levels of a number of angiogenic factors and their soluble receptors in preeclampsia. In this study, we examined the mechanism of production of soluble Tie2 (sTie2) and its potential connection to the failure of vascular remodeling in preeclamptic pregnancies.

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