The Regulation of Vascular Endothelial Growth Factor by Hypoxia and Prostaglandin F2αduring Human Endometrial Repair | Zendy

Jacqueline A. Maybin | Zendy; Nikhil Hirani | Zendy; Pamela Brown | Zendy; Henry N. Jabbour | Zendy; Hilary Critchley | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

The Regulation of Vascular Endothelial Growth Factor by Hypoxia and Prostaglandin F_2αduring Human Endometrial Repair

Author(s) -

Jacqueline A. Maybin,

Nikhil Hirani,

Pamela Brown,

Henry N. Jabbour,

Hilary Critchley

Publication year - 2011

Publication title -

the journal of clinical endocrinology and metabolism

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.206

H-Index - 353

eISSN - 1945-7197

pISSN - 0021-972X

DOI - 10.1210/jc.2010-2971

Subject(s) - vascular endothelial growth factor , hypoxia (environmental) , medicine , endocrinology , stromal cell , angiogenesis , endometrium , prostaglandin , vascular endothelial growth factor a , biology , andrology , chemistry , vegf receptors , organic chemistry , oxygen

The human endometrium has an exceptional capacity for repeated repair after menses, but its regulation remains undefined. Premenstrually, progesterone levels fall and prostaglandin (PG) F₂α synthesis increases, causing spiral arteriole constriction. We hypothesized that progesterone withdrawal, PGF₂α, and hypoxia increase vascular endothelial growth factor (VEGF), an endometrial repair factor.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research