Higher Maternal Gestational Glucose Concentration Is Associated with Lower Offspring Insulin Sensitivity and Altered β-Cell Function | Zendy

Nikki C. Bush | Zendy; Paula ChandlerLaney | Zendy; Dwight J. Rouse | Zendy; Wesley M. Granger | Zendy; Robert A. Oster | Zendy; Barbara A. Gower | Zendy

Open Access

Higher Maternal Gestational Glucose Concentration Is Associated with Lower Offspring Insulin Sensitivity and Altered β-Cell Function

Author(s) -

Nikki C. Bush,

Paula ChandlerLaney,

Dwight J. Rouse,

Wesley M. Granger,

Robert A. Oster,

Barbara A. Gower

Publication year - 2011

Publication title -

the journal of clinical endocrinology and metabolism

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.206

H-Index - 353

eISSN - 1945-7197

pISSN - 0021-972X

DOI - 10.1210/jc.2010-2902

Subject(s) - medicine , endocrinology , offspring , insulin , gestational diabetes , gestation , insulin resistance , glucose tolerance test , pregnancy , pancreatic hormone , fetus , biology , genetics

Intrauterine exposure to elevated glucose concentrations may be a mediating factor in prenatal programming of offspring diabetes risk. However, studies examining the effects of maternal glucose concentration on measures of insulin sensitivity and β-cell response in prepubertal children are limited.

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