Citrus Polyphenol Hesperidin Stimulates Production of Nitric Oxide in Endothelial Cells while Improving Endothelial Function and Reducing Inflammatory Markers in Patients with Metabolic Syndrome
Author(s) -
Stefano Rizza,
Ranganath Muniyappa,
Micaela Iantorno,
Jeonga Kim,
Hui Chen,
Philomena Pullikotil,
Nicoletta Senese,
Manfredi Tesauro,
Davide Lauro,
Carmine Cardillo,
Michael J. Quon
Publication year - 2011
Publication title -
the journal of clinical endocrinology and metabolism
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.206
H-Index - 353
eISSN - 1945-7197
pISSN - 0021-972X
DOI - 10.1210/jc.2010-2879
Subject(s) - hesperidin , hesperetin , endothelial dysfunction , pharmacology , medicine , endothelium , nitric oxide , inflammation , endocrinology , pathology , alternative medicine
Hesperidin, a citrus flavonoid, and its metabolite hesperetin may have vascular actions relevant to their health benefits. Molecular and physiological mechanisms of hesperetin actions are unknown.
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