Open AccessPolymorphisms in theSHBGGene Influence Serum SHBG Levels in Women with Polycystic Ovary Syndrome
Author(s) -
Edmond P. Wickham,
Kathryn G. Ewens,
Richard S. Legro,
Andrea Dunaif,
John E. Nestler,
Jerome F. Strauss
Publication year - 2011
Publication title -
the journal of clinical endocrinology and metabolism
Language(s) - English
Resource type - Journals
eISSN - 1945-7197
pISSN - 0021-972X
DOI - 10.1210/jc.2010-1842
Subject(s) - sex hormone binding globulin , polycystic ovary , single nucleotide polymorphism , insulin resistance , endocrinology , medicine , biology , genotype , genetics , androgen , insulin , gene , hormone
Single-nucleotide polymorphisms (SNPs) in the SHBG gene are associated with type 2 diabetes mellitus. SHBG has also been proposed as a candidate gene for the polycystic ovary syndrome (PCOS).
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom