Activation of the Receptor for Advanced Glycation End Products System in Women with Severe Preeclampsia
Author(s) -
Emily A. Oliver,
Catalin S. Buhimschi,
Antonette T. Dulay,
Margaret A. Baumbusch,
Sonya S. AbdelRazeq,
Sarah Y. Lee,
Guomao Zhao,
Shichu Jing,
Christian M. Pettker,
Irina A. Buhimschi
Publication year - 2011
Publication title -
the journal of clinical endocrinology and metabolism
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.206
H-Index - 353
eISSN - 1945-7197
pISSN - 0021-972X
DOI - 10.1210/jc.2010-1418
Subject(s) - amniotic fluid , glycation , medicine , endocrinology , rage (emotion) , preeclampsia , placenta , biology , cord blood , xanthine oxidase , amnion , receptor , andrology , fetus , pregnancy , biochemistry , enzyme , genetics , neuroscience
Activation of the receptor for advanced glycation end products (RAGE) mediates cellular injury. Soluble forms of RAGE [soluble RAGE (sRAGE), endogenous secretory (esRAGE)] bind RAGE ligands, thereby preventing downstream signaling and damage.
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