Increased Activity of the Hypothalamic-Pituitary-Testicular Axis in Infancy Results in Increased Androgen Action in Premature Boys
Author(s) -
Tanja KuiriHänninen,
Raija Seuri,
Erja Tyrväinen,
Ursula Turpeinen,
Esa Hämäläinen,
UlfHåkan Stenman,
Leo Dunkel,
Ulla Sankilampi
Publication year - 2010
Publication title -
the journal of clinical endocrinology and metabolism
Language(s) - English
Resource type - Journals
eISSN - 1945-7197
pISSN - 0021-972X
DOI - 10.1210/jc.2010-1359
Subject(s) - testosterone (patch) , medicine , context (archaeology) , endocrinology , hypothalamic–pituitary–gonadal axis , androgen , gestational age , urinary system , hormone , luteinizing hormone , pregnancy , biology , paleontology , genetics
Transient activation of the hypothalamic-pituitary-gonadal (HPG) axis is observed in boys during the first months of life. Previous research suggests increased HPG axis activation in premature infants, but the physiological significance of this has not been studied.
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