The Impact of Genetic Variation in theG6PC2Gene on Insulin Secretion Depends on Glycemia | Zendy

Martin Heni | Zendy; Caroline Ketterer | Zendy; Leen M. ‘t Hart | Zendy; Felicia Ranta | Zendy; Timon W. van Haeften | Zendy; Elisabeth M. W. Eekhoff | Zendy; Joost Dekker | Zendy; Dorret I. Boomsma | Zendy; Giel Nijpels | Zendy; Mark H.H. Kramer | Zendy; Michaëla Diamant | Zendy; Annemarie M. Simonis-Bik | Zendy; Robert J. Heine | Zendy; Eco J. C. de Geus | Zendy; Silke Schäfer | Zendy; Fausto Machicao | Zendy; Susanne Ullrich | Zendy; Claus Thamer | Zendy; Norbert Stefan | Zendy; Harald Staiger | Zendy; HansUlrich Häring | Zendy; Andreas Fritsche | Zendy

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The Impact of Genetic Variation in theG6PC2Gene on Insulin Secretion Depends on Glycemia

Author(s) -

Martin Heni,

Caroline Ketterer,

Leen M. ‘t Hart,

Felicia Ranta,

Timon W. van Haeften,

Elisabeth M. W. Eekhoff,

Joost Dekker,

Dorret I. Boomsma,

Giel Nijpels,

Mark H.H. Kramer,

Michaëla Diamant,

Annemarie M. Simonis-Bik,

Robert J. Heine,

Eco J. C. de Geus,

Silke Schäfer,

Fausto Machicao,

Susanne Ullrich,

Claus Thamer,

Norbert Stefan,

Harald Staiger,

HansUlrich Häring,

Andreas Fritsche

Publication year - 2010

Publication title -

the journal of clinical endocrinology and metabolism

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.206

H-Index - 353

eISSN - 1945-7197

pISSN - 0021-972X

DOI - 10.1210/jc.2010-0860

Subject(s) - medicine , endocrinology , impaired glucose tolerance , single nucleotide polymorphism , insulin , type 2 diabetes , insulin resistance , minor allele frequency , diabetes mellitus , glucose clamp technique , glucose tolerance test , allele , snp , genotype , impaired fasting glucose , biology , pancreatic hormone , genetics , gene

Single-nucleotide polymorphisms (SNPs) within the G6PC2 locus are associated with fasting glucose and insulin secretion. These SNPs are not associated with type 2 diabetes risk.

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