Open AccessCortisol Stimulates Secretion of Dehydroepiandrosterone in Human Adrenocortical Cells Through Inhibition of 3βHSD2
Author(s) -
Lisa Swartz Topor,
Masato Asai,
James Dunn,
Joseph A. Majzoub
Publication year - 2010
Publication title -
the journal of clinical endocrinology and metabolism
Language(s) - English
Resource type - Journals
eISSN - 1945-7197
pISSN - 0021-972X
DOI - 10.1210/jc.2010-0692
Subject(s) - dehydroepiandrosterone , endocrinology , secretion , medicine , chemistry , hormone , androgen
Initiating factors leading to production of adrenal androgens are poorly defined. Cortisol is present in high concentrations within the adrenal gland, and its production rises with growth during childhood.
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