Open Access25-Hydroxyvitamin D, Insulin-Like Growth Factor-I, and Bone Mineral Accrual during Growth
Author(s) -
M. E. Breen,
Emma Laing,
Daniel B. Hall,
Dorothy B. Hausman,
Ruth G. Taylor,
Carlos M. Isales,
Ke Ding,
Norman K. Pollock,
Mark W. Hamrick,
Clifton A. Baile,
Richard D. Lewis
Publication year - 2011
Publication title -
the journal of clinical endocrinology and metabolism/journal of clinical endocrinology and metabolism
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.206
H-Index - 353
eISSN - 1945-7197
pISSN - 0021-972X
DOI - 10.1210/jc.2010-0595
Subject(s) - medicine , endocrinology , insulin like growth factor , accrual , vitamin d and neurology , bone mineral , analysis of variance , repeated measures design , growth factor , osteoporosis , receptor , mathematics , statistics , accounting , earnings , business
The extent to which 25-hydroxyvitamin D [25(OH)D] and IGF-I influence bone mineral content (BMC) accrual from early to mid-puberty is unclear. OBJECTIVE, SETTING, AND PARTICIPANTS: This study sought to determine relationships among 25(OH)D, IGF-I, and BMC in community-dwelling prepubertal females (n = 76; aged 4-8 yr at baseline) over a period of up to 9 yr.