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Circulating Levels of Soluble Klotho and FGF23 in X-Linked Hypophosphatemia: Circadian Variance, Effects of Treatment, and Relationship to Parathyroid Status
Author(s) -
Thomas O. Carpenter,
Karl Insogna,
Jane H. Zhang,
Bruce Ellis,
Sherril D. Nieman,
Christine Simpson,
Elizabeth Olear,
Caren M. Gundberg
Publication year - 2010
Publication title -
the journal of clinical endocrinology and metabolism
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.206
H-Index - 353
eISSN - 1945-7197
pISSN - 0021-972X
DOI - 10.1210/jc.2010-0589
Subject(s) - hypophosphatemia , klotho , medicine , fibroblast growth factor 23 , endocrinology , circadian rhythm , parathyroid hormone , kidney , calcium
Circulating fibroblast growth factor (FGF)-23 is variably elevated in individuals with X-linked hypophosphatemia (XLH), and klotho has recently been shown to effect renal phosphate handling, yet limited data are available on circulating FGF23 and klotho in XLH.

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