Acid-Labile Subunit (ALS) Gene Expression and Protein Content in Human Placentas: Differences According to Birth Weight | Zendy

Germán Iñíguez | Zendy; F. Argandoña | Zendy; Pablo Medina | Zendy; Carolina González | Zendy; Sebastián San Martín | Zendy; Elena Kakarieka | Zendy; M. Cecilia Johnson | Zendy; Fernando Cassorla | Zendy

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Acid-Labile Subunit (ALS) Gene Expression and Protein Content in Human Placentas: Differences According to Birth Weight

Author(s) -

Germán Iñíguez,

F. Argandoña,

Pablo Medina,

Carolina González,

Sebastián San Martín,

Elena Kakarieka,

M. Cecilia Johnson,

Fernando Cassorla

Publication year - 2010

Publication title -

the journal of clinical endocrinology and metabolism

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.206

H-Index - 353

eISSN - 1945-7197

pISSN - 0021-972X

DOI - 10.1210/jc.2010-0244

Subject(s) - placenta , messenger rna , medicine , endocrinology , protein subunit , biology , small for gestational age , gene expression , andrology , gestation , gene , fetus , pregnancy , biochemistry , genetics

In humans, IGF-I and -II have an important role in pre- and postnatal growth. The IGFs circulate in plasma principally as a ternary complex with the IGF binding protein-3 and an acid-labile subunit (ALS), which increases their half life.

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