Reduced Glucose Tolerance and Insulin Resistance Induced by Steroid Treatment, Relative Physical Inactivity, and High-Calorie Diet Impairs the Incretin Effect in Healthy Subjects
Author(s) -
Katrine Bagge Hansen,
Tina Vilsbøll,
Jonatan I. Bagger,
Jens J. Holst,
Filip K. Knop
Publication year - 2010
Publication title -
the journal of clinical endocrinology and metabolism
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.206
H-Index - 353
eISSN - 1945-7197
pISSN - 0021-972X
DOI - 10.1210/jc.2010-0119
Subject(s) - medicine , incretin , endocrinology , insulin resistance , glucose homeostasis , impaired glucose tolerance , diabetes mellitus , type 2 diabetes , insulin , glucose tolerance test , calorie
The loss of incretin effect in patients with type 2 diabetes mellitus may be secondary to impaired glucose homeostasis. We investigated whether reduced glucose tolerance and insulin resistance induced by steroid treatment, relative physical inactivity, and high-calorie diet in healthy young males would impair the incretin effect.
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