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Amniotic Fluid Angiopoietin-1, Angiopoietin-2, and Soluble Receptor Tunica Interna Endothelial Cell Kinase-2 Levels and Regulation in Normal Pregnancy and Intraamniotic Inflammation-Induced Preterm Birth
Author(s) -
Catalin S. Buhimschi,
Vineet Bhandari,
Antonette T. Dulay,
Stephen Thung,
Sonya S. Abdel- Razeq,
Victor Rosenberg,
Christina S. Han,
Unzila Ali,
Eduardo Zambrano,
Guomao Zhao,
Edmund F. Funai,
Irina A. Buhimschi
Publication year - 2010
Publication title -
the journal of clinical endocrinology and metabolism
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.206
H-Index - 353
eISSN - 1945-7197
pISSN - 0021-972X
DOI - 10.1210/jc.2009-2829
Subject(s) - placenta , amniotic fluid , endocrinology , medicine , angiopoietin receptor , angiopoietin , amnion , angiotensin converting enzyme 2 , pregnancy , receptor , andrology , fetus , biology , vascular endothelial growth factor , genetics , vegf receptors , disease , covid-19 , infectious disease (medical specialty)
Angiopoietin-1 (Ang-1) and Ang-2 act selectively on endothelial cells by engaging the Tunica interna endothelial cell kinase-2 (Tie2) receptor. A soluble form of Tie2 (sTie2) blocks angiopoietin bioactivity.

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