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High Efficacy of Concomitant Treatment of Undifferentiated (Anaplastic) Thyroid Cancer with Radiation and Docetaxel
Author(s) -
Marlene Troch,
Oskar Koperek,
Christian Scheuba,
Karin Dieckmann,
Martha Hoffmann,
Bruno Niederle,
Markus Raderer
Publication year - 2010
Publication title -
the journal of clinical endocrinology and metabolism
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.206
H-Index - 353
eISSN - 1945-7197
pISSN - 0021-972X
DOI - 10.1210/jc.2009-2827
Subject(s) - docetaxel , anaplastic thyroid cancer , concomitant , medicine , context (archaeology) , oncology , external beam radiation , thyroid cancer , radiation therapy , thyroid , cancer research , chemotherapy , biology , paleontology
Anaplastic thyroid carcinoma (ATC) is a rare but aggressive solid tumor with a very short survival time even with multimodality treatment. In view of in vitro data and the high rate of p53 mutations in ATC, we have used combined treatment with external beam radiation and docetaxel.

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