Open AccessBRAFV600E Mutation Analysis in Fine-Needle Aspiration Cytology Specimens for Evaluation of Thyroid Nodule: A Large Series in aBRAFV600E-Prevalent Population
Author(s) -
Sun Wook Kim,
Ji In Lee,
JongWon Kim,
ChangSeok Ki,
Young Lyun Oh,
YoonLa Choi,
Jung Hee Shin,
Hee Kyung Kim,
Hye Won Jang,
Jae Hoon Chung
Publication year - 2010
Publication title -
the journal of clinical endocrinology and metabolism
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.206
H-Index - 353
eISSN - 1945-7197
pISSN - 0021-972X
DOI - 10.1210/jc.2009-2795
Subject(s) - thyroid carcinoma , thyroid nodules , medicine , mutation testing , fine needle aspiration , thyroid , mutation , nodule (geology) , population , cytology , pathology , multiplex , v600e , radiology , biopsy , biology , gene , bioinformatics , genetics , paleontology , environmental health
The BRAFV600E mutation is highly specific to papillary thyroid carcinoma. A test for this mutation may increase the diagnostic accuracy of fine-needle aspiration cytology (FNAC), especially in a BRAFV600E mutation-prevalent population.
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