Open AccessThe Exon 3 Deleted Growth Hormone Receptor Gene Is Associated with Small Birth Size and Early Pubertal Onset in Healthy Boys
Author(s) -
Kaspar Sørensen,
Lise Aksglæde,
Jørgen Holm Petersen,
Henrik Leffers,
Anders Juul
Publication year - 2010
Publication title -
the journal of clinical endocrinology and metabolism
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.206
H-Index - 353
eISSN - 1945-7197
pISSN - 0021-972X
DOI - 10.1210/jc.2009-2484
Subject(s) - exon , gene , genetics , growth hormone , biology , hormone , medicine , endocrinology
The GH/IGF-I axis influences gonadal development and function. Recently, a deletion of exon 3 in the GH receptor gene (GHRd3) has been linked to increased responsiveness to GH.
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