Indices of Cholesterol Metabolism and Relative Responsiveness to Ezetimibe and Simvastatin
Author(s) -
Susan G. Lakoski,
Fang Xu,
Gloria Lena Vega,
Scott M. Grundy,
Manisha Chandalia,
Chun Sing Lam,
Robert S. Lowe,
Michael Stepanavage,
MingShyan Lin,
Jonathan C. Cohen,
Helen H. Hobbs
Publication year - 2009
Publication title -
the journal of clinical endocrinology and metabolism
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.206
H-Index - 353
eISSN - 1945-7197
pISSN - 0021-972X
DOI - 10.1210/jc.2009-1952
Subject(s) - ezetimibe , simvastatin , lathosterol , pcsk9 , campesterol , placebo , cholesterol , medicine , endocrinology , statin , pharmacology , crossover study , lipoprotein , chemistry , sterol , ldl receptor , alternative medicine , pathology
The level and duration of exposure to circulating low-density lipoprotein-cholesterol (LDL-C) are major contributors to coronary atherosclerosis. Therefore, optimal prevention will require long-term LDL-C reduction, making it important to select the most effective agent for each individual.
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