Open AccessThe Common Genetic Variant of Luteinizing Hormone Has a Longer Serum Half-Life than the Wild Type in Heterozygous Women
Author(s) -
Leif Wide,
Karin Eriksson,
Patrick M. Sluss,
Janet E. Hall
Publication year - 2009
Publication title -
the journal of clinical endocrinology and metabolism
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.206
H-Index - 353
eISSN - 1945-7197
pISSN - 0021-972X
DOI - 10.1210/jc.2009-1679
Subject(s) - sialic acid , endocrinology , medicine , context (archaeology) , wild type , luteinizing hormone , receptor , chemistry , gene isoform , biology , hormone , biochemistry , gene , mutant , paleontology
The common genetic variant of human LH has two mutations and an extra N-linked oligosaccharide chain, a modification expected to affect the half-life in the circulation.
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