Open AccessEffect of Short-Term Free Fatty Acids Elevation on Mitochondrial Function in Skeletal Muscle of Healthy Individuals
Author(s) -
Alberto O. Chávez,
Subhash Kamath,
Rucha Jani,
Lokendra Sharma,
Adriana Monroy,
Muhammad AbdulGhani,
Victoria E. Centonze,
Padma Sathyanarayana,
Dawn K. Coletta,
Cristopher P. Jenkinson,
Yidong Bai,
Franco Folli,
Ralph A. DeFronzo,
Devjit Tripathy
Publication year - 2009
Publication title -
the journal of clinical endocrinology and metabolism
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.206
H-Index - 353
eISSN - 1945-7197
pISSN - 0021-972X
DOI - 10.1210/jc.2009-1387
Subject(s) - medicine , endocrinology , insulin resistance , mitochondrion , saline , skeletal muscle , fatty acid , insulin , citrate synthase , lipid metabolism , biology , glucose clamp technique , chemistry , pancreatic hormone , biochemistry , enzyme
Mitochondrial dysfunction has been proposed as an underlying mechanism in the pathogenesis of insulin resistance and type 2 diabetes mellitus.
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