Obese Children with Low Birth Weight Demonstrate Impaired β-Cell Function during Oral Glucose Tolerance Test
Author(s) -
Claudia Brufani,
Armando Grossi,
Danilo Fintini,
Alberto Eugenio Tozzi,
Valentiocerino,
Patrizia Ippolita Patera,
Graziamaria Ubertini,
Ottavia Porzio,
Fabrizio Barbetti,
Marco Cappa
Publication year - 2009
Publication title -
the journal of clinical endocrinology and metabolism
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.206
H-Index - 353
eISSN - 1945-7197
pISSN - 0021-972X
DOI - 10.1210/jc.2009-1079
Subject(s) - impaired glucose tolerance , medicine , low birth weight , glucose tolerance test , test (biology) , function (biology) , endocrinology , obesity , biology , pregnancy , insulin resistance , genetics , paleontology
Epidemiological studies have shown an association between birth weight and future risk of type 2 diabetes, with individuals born either small or large for gestational age at increased risk. We sought to investigate the influence of birth weight on the relation between insulin sensitivity and beta-cell function in obese children.
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