Unraveling the Directional Link between Adiposity and Inflammation: A Bidirectional Mendelian Randomization Approach
Author(s) -
Paul Welsh,
Eliana Polisecki,
Michele Robertson,
Sabine Jahn,
Brendan M. Buckley,
Anton J.M. de Craen,
Ian Ford,
J. Wouter Jukema,
Peter W. Macfarlane,
Chris J. Packard,
David J. Stott,
Rudi G. J. Westendorp,
James Shepherd,
Aroon D. Hingorani,
George Davey Smith,
Ernst J. Schaefer,
Naveed Sattar
Publication year - 2009
Publication title -
the journal of clinical endocrinology and metabolism
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.206
H-Index - 353
eISSN - 1945-7197
pISSN - 0021-972X
DOI - 10.1210/jc.2009-1064
Subject(s) - mendelian randomization , medicine , endocrinology , single nucleotide polymorphism , body mass index , leptin , context (archaeology) , allele , inflammation , obesity , c reactive protein , liter , biology , genotype , genetics , gene , genetic variants , paleontology
Associations between adiposity and circulating inflammation markers are assumed to be causal, although the direction of the relationship has not been proven.
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