Increased Prevalance of the −211 T Allele of Follicle Stimulating Hormone (FSH) β Subunit Promoter Polymorphism and Lower Serum FSH in Infertile Men | Zendy

Marina Grigorova | Zendy; Margus Punab | Zendy; Olev Poolamets | Zendy; Piret Kelgo | Zendy; Kristo Ausmees | Zendy; Paul Korrovits | Zendy; Vladimir Vihljajev | Zendy; Maris Laan | Zendy

Open Access

Increased Prevalance of the −211 T Allele of Follicle Stimulating Hormone (FSH) β Subunit Promoter Polymorphism and Lower Serum FSH in Infertile Men

Author(s) -

Marina Grigorova,

Margus Punab,

Olev Poolamets,

Piret Kelgo,

Kristo Ausmees,

Paul Korrovits,

Vladimir Vihljajev,

Maris Laan

Publication year - 2009

Publication title -

the journal of clinical endocrinology and metabolism

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.206

H-Index - 353

eISSN - 1945-7197

pISSN - 0021-972X

DOI - 10.1210/jc.2009-1010

Subject(s) - follicle stimulating hormone , endocrinology , medicine , allele , polymorphism (computer science) , hormone , andrology , biology , luteinizing hormone , gene , genetics

The human FSHB promoter polymorphism (rs10835638; -211 G/T) has been associated with serum FSH in a cohort of young Estonian men. The minor allele carriers had reduced serum FSH (15.7% in GT heterozygotes; 40% in TT homozygotes) compared with GG homozygotes.

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