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Microchimerism is the presence of small populations of cells from one individual in another genetically distinct individual. This phenomenon can arise from pregnancy, blood transfusion, or bidirectional cell trafficking between twins in utero. Microchimerism has recently been proposed to play a role in the pathogenesis of thyroid autoimmunity. In that case, twins from opposite-sex pairs (OS) should have an increased risk of thyroid autoantibodies (TA).

the journal of clinical endocrinology and metabolism/journal of clinical endocrinology and metabolism

Aggregation of Thyroid Autoantibodies in Twins from Opposite-Sex Pairs Suggests that Microchimerism May Play a Role in the Early Stages of Thyroid Autoimmunity