Adipocyte Differentiation-Related Protein and OXPAT in Rat and Human Skeletal Muscle: Involvement in Lipid Accumulation and Type 2 Diabetes Mellitus | Zendy

Ronnie Minnaard | Zendy; Patrick Schrauwen | Zendy; Gert Schaart | Zendy; Johanna A. Jörgensen | Zendy; Ellen Lenaers | Zendy; Marco Mensink | Zendy; Matthijs K. C. Hesselink | Zendy

Open Access

Adipocyte Differentiation-Related Protein and OXPAT in Rat and Human Skeletal Muscle: Involvement in Lipid Accumulation and Type 2 Diabetes Mellitus

Author(s) -

Ronnie Minnaard,

Patrick Schrauwen,

Gert Schaart,

Johanna A. Jörgensen,

Ellen Lenaers,

Marco Mensink,

Matthijs K. C. Hesselink

Publication year - 2009

Publication title -

the journal of clinical endocrinology and metabolism

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.206

H-Index - 353

eISSN - 1945-7197

pISSN - 0021-972X

DOI - 10.1210/jc.2009-0352

Subject(s) - endocrinology , medicine , insulin resistance , skeletal muscle , perilipin , lipid metabolism , lipid droplet , type 2 diabetes , adipocyte , insulin , diabetes mellitus , biology , chemistry , adipose tissue

A disordered lipid metabolism is implicated in the development of skeletal muscle insulin resistance. Lipid droplet proteins of the PAT [perilipin, adipocyte differentiation-related protein (ADRP), and TIP47] family have been shown to regulate lipid accumulation and intracellular metabolism in other tissues.

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