Open AccessTestosterone’s Short-Term Positive Effect on Luteinizing-Hormone Secretory-Burst Mass and Its Negative Effect on Secretory-Burst Frequency Are Attenuated in Middle-Aged Men
Author(s) -
Yang Liu,
Paul Y. Takahashi,
Pamela D. Roebuck,
James Bailey,
Daniel M. Keenan,
Johannes D. Veldhuis
Publication year - 2009
Publication title -
the journal of clinical endocrinology and metabolism/journal of clinical endocrinology and metabolism
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.206
H-Index - 353
eISSN - 1945-7197
pISSN - 0021-972X
DOI - 10.1210/jc.2009-0135
Subject(s) - endocrinology , medicine , testosterone (patch) , pulsatile flow , luteinizing hormone , basal (medicine) , androgen , hormone , biology , insulin
Testosterone (T) production declines and LH pulses become smaller and more frequent in middle-aged men. The mechanisms underlying these changes are not known.