Autoimmune Thyroiditis and Diabetes: Dissecting the Joint Genetic Susceptibility in a Large Cohort of Multiplex Families | Zendy

Maria Justina B. Villano | Zendy; Amanda K. Huber | Zendy; David A. Greenberg | Zendy; Brian K. Golden | Zendy; Erlinda Concepcion | Zendy; Yaron Tomer | Zendy

Open Access

Autoimmune Thyroiditis and Diabetes: Dissecting the Joint Genetic Susceptibility in a Large Cohort of Multiplex Families

Author(s) -

Maria Justina B. Villano,

Amanda K. Huber,

David A. Greenberg,

Brian K. Golden,

Erlinda Concepcion,

Yaron Tomer

Publication year - 2009

Publication title -

the journal of clinical endocrinology and metabolism

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.206

H-Index - 353

eISSN - 1945-7197

pISSN - 0021-972X

DOI - 10.1210/jc.2008-2193

Subject(s) - medicine , type 1 diabetes , thyroiditis , context (archaeology) , autoimmune thyroiditis , immunology , multiplex , genetic predisposition , autoimmune disease , disease , autoimmune diabetes , cohort , epidemiology , diabetes mellitus , genetics , endocrinology , biology , paleontology

Epidemiological data support a shared genetic susceptibility to autoimmune thyroid disease (AITD) and type 1 diabetes (T1D). Both diseases frequently occur within the same family and in the same individual. Patients developing both T1D and AITD are considered to have an autoimmune polyglandular syndrome type 3 variant (APS3v).

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