Vildagliptin Enhances Islet Responsiveness to Both Hyper- and Hypoglycemia in Patients with Type 2 Diabetes | Zendy

Bo Åhrén | Zendy; Anja Schweizer | Zendy; S. Dejager | Zendy; Beth E. Dunning | Zendy; Peter M. Nilsson | Zendy; Margaretha Persson | Zendy; James E. Foley | Zendy

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Vildagliptin Enhances Islet Responsiveness to Both Hyper- and Hypoglycemia in Patients with Type 2 Diabetes

Author(s) -

Bo Åhrén,

Anja Schweizer,

S. Dejager,

Beth E. Dunning,

Peter M. Nilsson,

Margaretha Persson,

James E. Foley

Publication year - 2009

Publication title -

the journal of clinical endocrinology and metabolism

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.206

H-Index - 353

eISSN - 1945-7197

pISSN - 0021-972X

DOI - 10.1210/jc.2008-2152

Subject(s) - vildagliptin , glucagon , hypoglycemia , medicine , endocrinology , crossover study , type 2 diabetes , diabetes mellitus , liter , placebo , glucose clamp technique , insulin , pancreatic hormone , insulin resistance , alternative medicine , pathology

Dipeptidyl peptidase-4 inhibitors act by increasing plasma levels of glucagon-like peptide-1 and suppressing excessive glucagon secretion in patients with type 2 diabetes. However, their effects on the glucagon response to hypoglycemia are not established.

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