Anti-Melanocortin-4 Receptor Autoantibodies in Obesity
Author(s) -
JeanChristophe Peter,
Akkiz Bekel,
Anne-Catherine Lecourt,
Géraldine Zipfel,
Pierre Eftekhari,
Maya Nesslinger,
Matthias Breidert,
Sylviane Muller,
L. Kessler,
Karl G. Hofbauer
Publication year - 2008
Publication title -
the journal of clinical endocrinology and metabolism
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.206
H-Index - 353
eISSN - 1945-7197
pISSN - 0021-972X
DOI - 10.1210/jc.2008-1749
Subject(s) - melanocortin 4 receptor , obesity , endocrinology , medicine , receptor , autoantibody , melanocortin , adenylyl cyclase , overweight , chemistry , biology , antibody , immunology
The melanocortin-4 receptor (MC4R) is part of an important pathway regulating energy balance. Here we report the existence of autoantibodies (autoAbs) against the MC4R in sera of obese patients.
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