Open AccessTranscriptional Profiling with a Pathway-Oriented Analysis Identifies Dysregulated Molecular Phenotypes in the Endometrium of Patients with Polycystic Ovary Syndrome
Author(s) -
Jin Yeong Kim,
Haengseok Song,
HyunJoo Kim,
Hee Jung Kang,
Jin Hyun Jun,
Sung Ran Hong,
Mi Kyoung Koong,
In Sun Kim
Publication year - 2009
Publication title -
the journal of clinical endocrinology and metabolism/journal of clinical endocrinology and metabolism
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.206
H-Index - 353
eISSN - 1945-7197
pISSN - 0021-972X
DOI - 10.1210/jc.2008-1612
Subject(s) - polycystic ovary , laser capture microdissection , biology , anovulation , endocrinology , endometrium , medicine , gene expression profiling , insulin resistance , gene expression , insulin , genetics , gene
Polycystic ovary syndrome (PCOS) is a common endocrine disorder characterized by chronic oligo/anovulation, hyperandrogenemia, infertility, and metabolic alterations related to insulin resistance. These abnormalities in PCOS may have complex effects on pathophysiology of the endometrium, contributing to infertility and endometrial disorders.