Insulin-Like Growth Factor Binding Protein 1 as a Novel Specific Marker of Hepatic Insulin Sensitivity | Zendy

Anna Kotronen | Zendy; Moira Lewitt | Zendy; Kerstin Hall | Zendy; Kerstin Brismar | Zendy; Hannele YkiJärvinen | Zendy

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Insulin-Like Growth Factor Binding Protein 1 as a Novel Specific Marker of Hepatic Insulin Sensitivity

Author(s) -

Anna Kotronen,

Moira Lewitt,

Kerstin Hall,

Kerstin Brismar,

Hannele YkiJärvinen

Publication year - 2008

Publication title -

the journal of clinical endocrinology and metabolism

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.206

H-Index - 353

eISSN - 1945-7197

pISSN - 0021-972X

DOI - 10.1210/jc.2008-1245

Subject(s) - medicine , endocrinology , insulin , triglyceride , body mass index , pancreatic hormone , insulin resistance , insulin like growth factor binding protein , obesity , glucose clamp technique , chemistry , insulin like growth factor , cholesterol , growth factor , receptor

The liver is the main source and insulin the main regulator of IGF binding protein 1 (IGFBP-1) in humans. Here we examined how serum IGFBP-1 concentrations are related to directly measured hepatic insulin sensitivity and liver fat content in humans.

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