Open AccessAnti-Mullerian Hormone, Its Receptor, FSH Receptor, and Androgen Receptor Genes Are Overexpressed by Granulosa Cells from Stimulated Follicles in Women with Polycystic Ovary Syndrome
Author(s) -
Sophie Catteau-Jonard,
Soazik P. Jamin,
Arnaud Leclerc,
Jacques Gonzalès,
Didier Dewailly,
Nathalie di Clemente
Publication year - 2008
Publication title -
the journal of clinical endocrinology and metabolism
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.206
H-Index - 353
eISSN - 1945-7197
pISSN - 0021-972X
DOI - 10.1210/jc.2008-1231
Subject(s) - polycystic ovary , anti müllerian hormone , endocrinology , medicine , follicle stimulating hormone receptor , granulosa cell , androgen receptor , hyperandrogenism , follicular phase , biology , ovary , androgen , andrology , follicle stimulating hormone , hormone , luteinizing hormone , insulin resistance , insulin , prostate cancer , cancer
In the polycystic ovary syndrome (PCOS), in addition to intrinsic thecal dysregulation leading to hyperandrogenism, a granulosa cell (GC) dysregulation may occur. Expression of anti-Müllerian hormone (AMH), FSH receptor (FSHR) and androgen receptor (AR) are suspected to be altered in PCOS GCs.
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