Glucocorticoid Receptor Gene Variant in the 3′ Untranslated Region Is Associated with Multiple Measures of Blood Pressure | Zendy

Charles C. Chung | Zendy; Lawrence C. Shimmin | Zendy; Sivamani Natarajan | Zendy; Craig L. Hanis | Zendy; Eric Boerwinkle | Zendy; James E. Hixson | Zendy

Open Access

Glucocorticoid Receptor Gene Variant in the 3′ Untranslated Region Is Associated with Multiple Measures of Blood Pressure

Author(s) -

Charles C. Chung,

Lawrence C. Shimmin,

Sivamani Natarajan,

Craig L. Hanis,

Eric Boerwinkle,

James E. Hixson

Publication year - 2008

Publication title -

the journal of clinical endocrinology and metabolism

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.206

H-Index - 353

eISSN - 1945-7197

pISSN - 0021-972X

DOI - 10.1210/jc.2008-1089

Subject(s) - blood pressure , single nucleotide polymorphism , biology , haplotype , endocrinology , allele , context (archaeology) , medicine , genetics , glucocorticoid receptor , pulse pressure , genotype , gene , glucocorticoid , paleontology

The glucocorticoid receptor (GR) is a key hormone in the hypothalamus-pituitary-adrenal axis that regulates many pathways including blood pressure homeostasis. Thus, GR gene variation may influence interindividual differences in blood pressure in human populations.

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