Open AccessSmall Vessel Remodeling and Impaired Endothelial-Dependent Dilatation in Subcutaneous Resistance Arteries from Patients with Acromegaly
Author(s) -
Angela Paisley,
Ashley S. Izzard,
Islay Gemmell,
Kennedy Cruickshank,
Peter Trainer,
Anthony M. Heagerty
Publication year - 2009
Publication title -
the journal of clinical endocrinology and metabolism
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.206
H-Index - 353
eISSN - 1945-7197
pISSN - 0021-972X
DOI - 10.1210/jc.2008-0948
Subject(s) - acromegaly , medicine , endocrinology , dilator , endothelial dysfunction , electrical impedance myography , contractility , vasodilation , growth hormone , hormone
Patients with acromegaly have increased morbidity and mortality, predominantly from cardiovascular disease. Hypertension and diabetes are more prevalent, and both cause small vessel remodeling and endothelial dysfunction.
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