Reduced Pancreatic Volume in Hepatocyte Nuclear Factor 1A-Maturity-Onset Diabetes of the Young
Author(s) -
Mette Vesterhus,
Ingfrid S. Haldorsen,
Helge Ræder,
Anders Molven,
Pål R. Njølstad
Publication year - 2008
Publication title -
the journal of clinical endocrinology and metabolism
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.206
H-Index - 353
eISSN - 1945-7197
pISSN - 0021-972X
DOI - 10.1210/jc.2008-0340
Subject(s) - diabetes mellitus , context (archaeology) , medicine , pancreas , hnf1a , endocrine system , endocrinology , hepatocyte nuclear factors , exocrine pancreas , biology , hormone , transcription factor , paleontology , biochemistry , gene
There are interplays between the endocrine and exocrine pancreas. We recently reported an increased frequency of exocrine dysfunction in HNF1A-maturity-onset diabetes of the young (MODY3) patients, compared with controls. Reduced pancreatic volume is seen in HNF1B-MODY (MODY5) and diabetes types 1 and 2.
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