Amniotic Fluid and Umbilical Cord Plasma Corticotropin-Releasing Factor (CRF), CRF-Binding Protein, Adrenocorticotropin, and Cortisol Concentrations in Intraamniotic Infection and Inflammation at Term
Author(s) -
Pasquale Florio,
Roberto Romero,
Tinnakorn Chaiworapongsa,
Juan Pedro Kusanovic,
Michela Torricelli,
P. J. Lowry,
Felice Petraglia
Publication year - 2008
Publication title -
the journal of clinical endocrinology and metabolism
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.206
H-Index - 353
eISSN - 1945-7197
pISSN - 0021-972X
DOI - 10.1210/jc.2007-2843
Subject(s) - endocrinology , medicine , amniotic fluid , context (archaeology) , inflammation , urocortin , corticotropin releasing hormone , umbilical cord , secretion , fetus , biology , pregnancy , immunology , hormone , receptor , genetics , paleontology
Pregnant tissues express corticotropin-releasing factor (CRF), a peptide modulating fetal and placental ACTH and cortisol secretion. These actions are modulated by the locally expressed CRF-binding protein (CRF-BP).
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