Absence of an Acute Insulin Response Predicts Onset of Type 2 Diabetes in a Caucasian Population with Impaired Glucose Tolerance | Zendy

Giel Nijpels | Zendy; W. Boorsma | Zendy; Joost Dekker | Zendy; F. Hoeksema | Zendy; P.J. Kostense | Zendy; L.M. Bouter | Zendy; Robert J. Heine | Zendy

Open Access

Absence of an Acute Insulin Response Predicts Onset of Type 2 Diabetes in a Caucasian Population with Impaired Glucose Tolerance

Author(s) -

Giel Nijpels,

W. Boorsma,

Joost Dekker,

F. Hoeksema,

P.J. Kostense,

L.M. Bouter,

Robert J. Heine

Publication year - 2008

Publication title -

the journal of clinical endocrinology and metabolism

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.206

H-Index - 353

eISSN - 1945-7197

pISSN - 0021-972X

DOI - 10.1210/jc.2007-2837

Subject(s) - medicine , impaired glucose tolerance , endocrinology , insulin resistance , insulin , diabetes mellitus , population , type 2 diabetes , glucose clamp technique , impaired fasting glucose , type 2 diabetes mellitus , glucose tolerance test , body mass index , pancreatic hormone , environmental health

In persons with impaired glucose tolerance (IGT), both impaired insulin secretion and insulin resistance contribute to the conversion to type 2 diabetes mellitus (T2DM). However, few studies have used criterion standard measures to asses the predictive value of impaired insulin secretion and insulin resistance for the conversion to T2DM in a Caucasian IGT population.

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