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Identification ofLTBP2on Chromosome 14q as a Novel Candidate Gene for Bone Mineral Density Variation and Fracture Risk Association
Author(s) -
ChingLung Cheung,
Pak C. Sham,
Vivian Chan,
Andrew D. Paterson,
K.D.K. Luk,
Annie W.C. Kung
Publication year - 2008
Publication title -
the journal of clinical endocrinology and metabolism
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.206
H-Index - 353
eISSN - 1945-7197
pISSN - 0021-972X
DOI - 10.1210/jc.2007-2836
Subject(s) - candidate gene , quantitative trait locus , genetics , biology , single nucleotide polymorphism , haplotype , bone mineral , genetic linkage , locus (genetics) , genome wide association study , copy number variation , osteoporosis , bone density , medicine , gene , endocrinology , genotype , genome
Low bone mineral density (BMD) is a major risk factor for osteoporotic fracture. Chromosome 14q has previously been linked to BMD variation in several genome-wide linkage scans in Caucasian populations.

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