The Effect of Sports Injury on Insulin-Like Growth Factor-I and Type 3 Procollagen: Implications for Detection of Growth Hormone Abuse in Athletes | Zendy

Ioulietta ErotokritouMulligan | Zendy; E. Eryl Bassett | Zendy; Christiaan Bartlett | Zendy; David Cowan | Zendy; Cathy McHugh | Zendy; Rick Seah | Zendy; Benjamin L. Curtis | Zendy; Victoria Wells | Zendy; Kate Harrison | Zendy; Peter H. Sönksen | Zendy; R. I. G. Holt | Zendy

Open Access

The Effect of Sports Injury on Insulin-Like Growth Factor-I and Type 3 Procollagen: Implications for Detection of Growth Hormone Abuse in Athletes

Author(s) -

Ioulietta ErotokritouMulligan,

E. Eryl Bassett,

Christiaan Bartlett,

David Cowan,

Cathy McHugh,

Rick Seah,

Benjamin L. Curtis,

Victoria Wells,

Kate Harrison,

Peter H. Sönksen,

R. I. G. Holt

Publication year - 2008

Publication title -

the journal of clinical endocrinology and metabolism

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.206

H-Index - 353

eISSN - 1945-7197

pISSN - 0021-972X

DOI - 10.1210/jc.2007-2801

Subject(s) - medicine , false accusation , athletes , procollagen peptidase , musculoskeletal injury , endocrinology , physical therapy , psychology , pathology , social psychology , alternative medicine

A method to detect exogenously administered growth hormone (GH) based on the measurement of two GH-dependent markers, IGF-I and type 3 procollagen (P-III-P) has been proposed. Skeletal or soft tissue injury may alter these markers. Elevations in either of these proteins after injury might lead to a false accusation of doping with GH.

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