Baseline Characteristics and the Effects of Two Years of Growth Hormone (GH) Replacement Therapy in Adults with GH Deficiency Previously Treated for Acromegaly | Zendy

Lise-Lott Norrman | Zendy; Gudmundur Johannsson | Zendy; Katharina S. Sunnerhagen | Zendy; Johan Svensson | Zendy

Open Access

Baseline Characteristics and the Effects of Two Years of Growth Hormone (GH) Replacement Therapy in Adults with GH Deficiency Previously Treated for Acromegaly

Author(s) -

Lise-Lott Norrman,

Gudmundur Johannsson,

Katharina S. Sunnerhagen,

Johan Svensson

Publication year - 2008

Publication title -

the journal of clinical endocrinology and metabolism

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.206

H-Index - 353

eISSN - 1945-7197

pISSN - 0021-972X

DOI - 10.1210/jc.2007-2673

Subject(s) - acromegaly , medicine , endocrinology , context (archaeology) , diabetes mellitus , hyperlipidemia , hormone , growth hormone , biology , paleontology

The effects of GH replacement in GH-deficient (GHD) adults previously treated for acromegaly are not well known. OBJECTIVE, DESIGN, AND PATIENTS: In this single-center, open-labeled, prospective study, 10 consecutive GHD adults with cured acromegaly (A group) and 10 matched GHD adults with previous nonfunctioning hypopituitary disease (NF group) were included. Comparisons were made at baseline and in the responses in body composition, muscle strength, bone mass, and metabolic indices during 2 yr of GH replacement.

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