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The Role of the Aryl Hydrocarbon Receptor-Interacting Protein Gene in Familial and Sporadic Pituitary Adenomas
Author(s) -
Chrysanthia A. Leontiou,
Maria Gueorguiev,
Jacqueline van der Spuy,
Richard Quinton,
Francesca Lolli,
Sevda Hassan,
Harvinder Chahal,
Susana Igreja,
Suzanne Jordan,
Janice Rowe,
Marie Stolbrink,
Helen Christian,
Jessica A. Wray,
David BishopBailey,
Daniel M. Berney,
John Wass,
Vera Popović,
Antônio RibeiroOliveira,
Mônica R. Gadelha,
John P. Monson,
Scott Akker,
J.R. Davis,
Richard N. Clayton,
Katsuhiko Yoshimoto,
Takeo Iwata,
Akira Matsuno,
Kuniki Eguchi,
Mädälina Muşat,
Daniel Flanagan,
Gordon Peters,
Graeme B. Bolger,
J. Paul Chapple,
Lawrence A. Frohman,
Ashley Grossman,
Márta Korbonits
Publication year - 2008
Publication title -
the journal of clinical endocrinology and metabolism
Language(s) - English
Resource type - Journals
eISSN - 1945-7197
pISSN - 0021-972X
DOI - 10.1210/jc.2007-2611
Subject(s) - biology , pituitary adenoma , pituitary tumors , acromegaly , adenoma , endocrinology , microbiology and biotechnology , genetics , hormone , growth hormone
Mutations have been identified in the aryl hydrocarbon receptor-interacting protein (AIP) gene in familial isolated pituitary adenomas (FIPA). It is not clear, however, how this molecular chaperone is involved in tumorigenesis.

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