Open AccessElevated Midpregnancy Corticotropin-Releasing Hormone Is Associated with Prenatal, But Not Postpartum, Maternal Depression
Author(s) -
Janet W. RichEdwards,
Anshu P. Mohllajee,
Ken Kleinman,
Michele R. Hacker,
Joseph A. Majzoub,
Rosalind J. Wright,
Matthew W. Gillman
Publication year - 2008
Publication title -
the journal of clinical endocrinology and metabolism/journal of clinical endocrinology and metabolism
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.206
H-Index - 353
eISSN - 1945-7197
pISSN - 0021-972X
DOI - 10.1210/jc.2007-2535
Subject(s) - edinburgh postnatal depression scale , odds ratio , postpartum depression , pregnancy , medicine , obstetrics , depression (economics) , endocrinology , gestation , postpartum period , biology , genetics , macroeconomics , economics
Elevated hypothalamic CRH has been implicated in melancholic major depression in nonpregnant individuals, but the role of placental CRH in maternal prenatal and postpartum depression is largely unexplored.