CCAAT/Enhancer Binding Protein β Regulates Aromatase Expression via Multiple and Novel Cis-Regulatory Sequences in Uterine Leiomyoma | Zendy

Hiroshi Ishikawa | Zendy; Veysel Fencki | Zendy; Erica E. Marsh | Zendy; Ping Yin | Zendy; Dong Chen | Zendy; You-Hong Cheng | Zendy; Scott Reisterd | Zendy; Zhihong Lin | Zendy; Serdar E. Bulun | Zendy

Open Access

CCAAT/Enhancer Binding Protein β Regulates Aromatase Expression via Multiple and Novel Cis-Regulatory Sequences in Uterine Leiomyoma

Author(s) -

Hiroshi Ishikawa,

Veysel Fencki,

Erica E. Marsh,

Ping Yin,

Dong Chen,

You-Hong Cheng,

Scott Reisterd,

Zhihong Lin,

Serdar E. Bulun

Publication year - 2008

Publication title -

the journal of clinical endocrinology and metabolism

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.206

H-Index - 353

eISSN - 1945-7197

pISSN - 0021-972X

DOI - 10.1210/jc.2007-2507

Subject(s) - aromatase , uterine leiomyoma , enhancer , ccaat enhancer binding proteins , leiomyoma , regulatory sequence , biology , microbiology and biotechnology , gene expression , gene , medicine , dna binding protein , transcription factor , genetics , pathology , breast cancer , cancer

Control of aromatase expression in uterine leiomyoma has significant clinical implications because aromatase inhibitors reduce tumor growth and associated irregular uterine bleeding. The mechanisms that regulate aromatase expression in leiomyoma are unknown.

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